Goofus, Gallant and You
One place I see this most frequently is when a donor makes a single gift for a special purpose - for example, a memorial gift or a sponsorship of a person participating in an event. Their loyalty for that gift may not be your organization, but rather the person they were giving on behalf of.
I am still receiving mailings from a major national organization to which I gave a memorialgift seven years ago. It even followed me halfway across the country. My total lack of response is a loud message - I am not interested in giving again. But because it has refused to listen for these many, many years, it has been diverting money from its important mission to stalk me.